But the cause is not always known. Dr. Aparna Singh presents a case of Mesial Temporal Sclerosis in which the symptoms were reversed with homeopathic treatment. Miasm consideration is not necessary, when the totality is characteristic and speaks for the remedy. It is important to clarify the nature of insults that most likely have ca… Histopathological hallmarks of hippocampal sclerosis include segmental loss of pyramidal neurons, granule cell dispersionand reactive gliosis. Mesial temporal sclerosis is the loss of neurons and scarring of the deepest portion of the temporal lobe and is associated with certain brain injuries. Mesial Temporal Sclerosis (MTS) is a term used to describe scarring in deep part of the temporal lobe of the brain. Symptoms of mesial temporal sclerosis are generally associated with focal (partial) epilepsy, such as. Fatigue Although the hippocampal sclerosis is commonly found among elderly people (≈10% of individuals over the age of 85 years), association between this disease and ageing remains unknown. I passed out from Nehru Homoeopathic Medical College in New Delhi in the May 1992 and earned a gold medallion for excellence in the academic study of Homoeopathy. On the other hand, it is an often unrecognized cause of cognitive decline, typically presenting with severe memory loss. During this time the feeling of coldness is so great that I have to cover the left side of my body with a blanket, even though it is the heat of summer, and the right side I leave uncovered. The neurophysician prescribed anti epileptic drugs. With no further repetition, I sent him away with placebo for 2 days. An amygdalohippocampectomy is the surgical removal of the amygdala and the hippocampus after other treatments have failed to provide relief. Our highly-qualified, board-certified neurosurgeons and epilepsy specialists provide expert mesial temporal sclerosis, hippocampal sclerosis, and associated temporal lobe epilepsy. Aft 2 days he came back and said, “Now the gap in between the episodes has increased, and also the intensity of symptoms is much less. This is a community dedicated to those of us who suffer with Mesial Temporal Sclerosis. Case Report: A 38 yr old male who was overweight had been seeing me for the past 10 years off and on for his health issues, mainly ureteric calculi, and pain in the renal region, at times left and other times right. There is slight dilatation of the right temporal horn as compared to the left. Seizures. Brain damage from traumatic injury, infection, a brain tumor, a lack of oxygen to the brain, or uncontrolled seizures is thought to cause the scar tissue to form, particularly in the hippocampus, a region of the temporal lobe. I love to experience nature with all its flora and fauna. TLE and mesial temporal sclerosis (MTS) were characterized by significant increases in OSTOX (MDA, AOPP, LOOH) and lowered ANTIOX (-SH groups, TRAP). Gelsemium is the perfect match (coldness, shivering, wave like sensation which travels up and down, slurring of speech, dull and lethargic). Apart from the chronic nature of epilepsy, hippocampal sclerosis was sho… Neuroimaging allows our expert brain surgeons to carefully target the damaged tissue and allow as much healthy brain tissue to remain as possible. MATERIAL AND METHODS . 1 Homeopathy Journal – It’s Free! Contact us today for an appointment or consultation. Seizure frequency is significantly associated with … Surgical treatments for intractable epilepsy include a temporal lobectomy or vagal nerve stimulation. Hippocampal sclerosis cases were more likely than Alzheimer’s disease to have had a history of stroke or hypertension, (evidence of small vessel disease) but less likely to have had diabetes mellitus. Apart from the chronic nature of epilepsy, hippocampal sclerosis was shown to have an important role in internal cardiac autonomic dysfunction. It can be a cause of seizures. He subsequently consulted a neurology specialist in the town. Columbia Resident Writes (a Chapter of) the Book on Cavernous Malformations Columbia Sends out Press Release on Department’s Aneurysm Research Columbia Spine Surgeons Mentioned in NJ Magazine Columbia Team Presents Picture of the Month in Archives of Pediatric Medicine Columbia to Host ‘Advances in Brain Tumor Management’ Symposium for Neurosurgeons Columbia Voted #1 Medical … MRI Report On 17th July 2014 after which antiepileptics were given. The percentage of seizure-free patients was 24.2% (22 of 91 patients) at the second visit which was held up to 5 years after the first visit. Mesial temporal sclerosis treatments generally consist of managing the epilepsy symptom by using either anticonvulsant medication or, if medication is not effective, surgery. Mesial temporal lobe sclerosis contributes to a significantly compromised quality of life for many patients. It just fit every bit of the puzzle. But the cause is not always known. 19 talking about this. He now complained of a headache whenever he woke up from sleep, on the left side of the head, dull aching and it would go off after about 1-2 hrs. Dr. Aparna Singh - I am a homoeopathic doctor practising this wonderful healing method for the past 23 years. Sudden or strange odor or taste 1.6. Mesial temporal sclerosis usually results in partial (focal) epilepsy. The area where the arrow points is the scarring of the neuronal tissue. Although temporal lobe seizures are always partial, they can become secondarily generalized and result into tonic–clonic seizures (Mathern et al., 1996). There is no blood flow obstruction, but the plain MRI still shows that atrophic scar in the deepest part of left temporal lobe. The region begins to atrophy; neurons die and scar tissue forms. Dr. Aparna Singh Temporal lobe seizures are often associated with auras of nausea, emotions (such … Follow up of children with febrile seizures does not demonstrate signifi… The next day he was discharged from the hospital and told that the ECG was normal and his symptoms were not related to cardiac cause. During this period, I have a feeling of anxiety and fear also. Talk to our Chatbot to narrow down your search. Connect today to learn how our award winning, world class experts can help. Patients with left hippocampal sclerosis had more severe parasympathetic dysfunction as compared with those with right hippocampal sclerosis. High anxiety symptoms are independently associated with epilepsy as well as focal/unknown epilepsy and mesial temporal sclerosis, according to study results published in Epilepsy & Behavior. My wife is 33 yr. Old. Hippocampal sclerosis also commonly referred to as mesial temporal sclerosis, is the most common brain pathological lesion underyling intractable temporal lobe epilepsy 1).. Hippocampal sclerosis is the commonest cause of drug-resistant epilepsy in adults, and is associated with alterations to structures and networks beyond the hippocampus 2). Sometimes a lack of oxygen, an infection, trauma or continuing seizures contribute to the development of mesial temporal sclerosis. On 16.04.17, she reported acute pain in lower left abdominal region and than fainted with biting of lips etc. Was achieved a bibliographic revision using Medline data base … Clinical presentation. Mesial temporal sclerosis (MTS), also commonly referred to as hippocampal sclerosis, is the most common association with intractable temporal lobe epilepsy (TLE) 2,3,5. He was rushed the same night to a nearby hospital for fear of a heart attack and was admitted for observation for the night to look for any cardiac cause. I feel sleepy and miserable after these drugs. Clinical studies suggest that prolonged seizures or complicated febrile seizures may result in MTS. On 15th July 2014, it was a hot summer day, and at noon he was riding his bike when he experienced some abnormal sensation of fluttering in the left side of his chest. All the symptoms have gone, and health is restored. Gelsemium and Lachesis are wonderful drugs. For Saltik et al. An aura or far-away look 1.2. Symptoms of mesial temporal sclerosis are generally associated with focal (partial) epilepsy, such as. This means that pyramidal neuronal cells are lost, granule cells are spread widely or driven off, and glial cells are changed in response to damage to the central nervous system (CNS). After about 40 minutes he got that conglomeration of signs and symptoms again, so the 1st improvement noticed was the time lag, instead of 20 minutes, it came aft 40 minutes. MRI voxel-based morphometry (VBM) of T1-weighted images has revealed a widespread pattern of gray matter (GM) and white matter (WM) atrophy in MTLE. This damage is thought to be a significant cause of temporal lobe epilepsy. MTS is the most common cause of structural epilepsy and focal seizures in the temporal lobe. 19, the febrile seizure is associated with MTS mainly when seizures start early or are present as complex febrile seizures or even as status febrile. consultation, Our Mesial temporal sclerosis (MTS), which involves neuronal loss and gliosis within the mesial temporal structures (primarily in Sommer sector and the CA4 region of the hippocampus), 1 is an important cause of temporal lobe epilepsy. Also since I am taking these anti-epileptic drugs, that neurologist has given me, now even if a dog barks, I get startled and fearful. Of note, sclerosis of mesial temporal lobe structures (mesial temporal sclerosis, MTS), ... 2000), sixty patients with TLE were subdivided according to mesial versus neocortical temporal sclerosis, and depressive symptoms were assessed using the self‐reported Beck Depression Inventory (BDI). MTLE typically causes seizures that last 30 seconds to two minutes and may include: 1. Moreover, a recent study revealed that 7 (41%) of 17 epilepsy patients with SLE had mesial temporal lobe epilepsy (MTLE) (Toyota et al., 2013). Hpathy Medical Publishers. More common are complex partial seizures (CPSs) in which the patients lose consciousness and have sensory, mental, visceral, and somatomotor symptoms. Copyright © 2020. my daughter(7 year old) was diagnosed that she as F/S/O Left mesial temporal sclerosis. A focal seizure in the temporal lobe may spread to other areas in the brain when it may become a focal to bilateral seizure. MTS affects the hippocampus which is the brain region that is involved in memory formation and retrieval and the amygdala which is involved in emotional processing. MRI scan commonly displays increased T2 signal and hippocampal atrophy Mesial temporal sclerosis might occur with other temporal lobe abnormalities (dual pathology). [casemed.case.edu] It is an important diagnosis to recognize as these patients can often be made seizure free with surgical resection of … I took MRI and test mentioned as follows “features are suggestive of right mesial temporal sclerosis”. After paying the bill of 15000/- Rs he went back home only to realise now that he also had a slur in his speech for those 2- 5 minutes when the abnormal sensations in his chest were experienced. The seizures usually are localized in the brain, but they may spread to become generalized seizures, which involve the entire brain and may cause a sudden loss of awareness or consciousness. Sex Males = females. Mesial temporal lobe epilepsy is the most common form of human epilepsy, and its pathophysiological substrate is usually hippocampal sclerosis, the most common epileptogenic lesion encountered in patients with epilepsy. Einteilung. He gets no exercise and has a fatty liver. The neurophysician ordered an MRI which revealed that there was scar/atrophic tissue/dead neuronal tissue, in the deepest part of the left temporal lobe/hippocampus. Under such a medical term as “hippocampal sclerosis”, specialists understand one of the forms of epileptic pathology caused by damage to the limbic system of the brain. The discrimination of pure TLE from controls yielded a significant area under the ROC curve for MDA (0.999), AOPP (0.851), -SH groups (0.899), and the OSTOX/ANTIOX ratio (0.996). Age at onset Late childhood or adolescence. … Hippocampal sclerosis. The changes associated with mesial temporal sclerosis are usually identifiable on a magnetic resonance imaging (MRI) scan. Homoeopathy is the science of symptoms. OBJECTIVE. For the past year he has been healthy otherwise. He has been in the habit of chewing gutka, (tobacco product) and paan masala (contains Betel leaf) for the past 6-8 yrs and also takes alcohol daily, for the past 3-4 years. Gelsemium LM2 was given twice a day, and on the 4th day he said- “I was feeling a lot better, the whole episode has almost vanished; there are no such symptoms of chilliness, wave etc, but now since the last dose I feel more lethargic and dull and tired , even though I felt better earlier.” In der Mehrzahl der Fälle liegt neuropathologisch eine mesiale temporale Sklerose vor, verändert sind der Hippocampus, die angrenzenden Hirnwindungen und der Mandelkern. I present cases in the IIHP meetings here in Dehradun, the capital of the Himalayan state of India, Uttarakhand. The hair on my left arm stands up (piloerection), and then a wave like sensation of fluttering originating from left side of chest and moving both up and down on left lower limb and left upper limb and towards the face, also left sided and lacrimation from left eye, and during this time I get that slurred speech if I try to speak. My family and I are in great distress, since I have been told by the neurologist that I am not supposed to drive, since I may black out and fall from a scooter or my car may meet an accident under the influence of these anti epileptics drugs. Unprovoked fear 2. Mesial temporal sclerosis is the most common pathological abnormality in temporal lobe epilepsy. Difficulty speaking 3.4. The peculiarity was that he would get this left sided headache even after he woke up from an afternoon nap. Hi mam, my son 13 yrs old boy. The seizures usually are localized in the brain, but they may spread to become generalized seizures, which involve the entire brain and may cause a sudden loss of awareness or consciousness. After the seizure: 3.1. He came to me on the 22nd of July 2014 and I asked him to explain in detail what he exactly felt in those 2 -5 minutes. However I want to ask you from which source book did you get the information on Gelsemium. I am in my forties now and have treated many complex cases. Checked Clarks Dictionary of Practical Materia Medica and could not find much. consultation, Request a For over 50 years & 350,000 patients NSPC has been a trusted global medical leader. Mesial Temporal Sclerosis Symptom Checker: Possible causes include Medial Sclerosis. For about 6 days the patient took those drugs only to realise that there was no reduction in those uncomfortable symptoms, and now some new symptoms had also come up. A far-away, glazed look 2.4. Neurological and mental state Usually normal prior to seizure onset. Remove from your own thinking disease/remedy relations, like for viral/ seasonal flus, Gels, Ars, Acon, or for joint pains, Rhus tox, Bry etc. An optimized high-resolution MRI, like the ones we use at our epilepsy centers in the NY area, can show mesial temporal sclerosis that other general MRIs often miss. Pl suggest. This seizure disorder can cause a variety of symptoms such as strange sensations, changes in behavior or emotions, muscle spasms, or convulsions.The seizures usually are localized in the brain, but they may spread to become generalized seizures, which involve the entire brain and may cause a sudden loss of awareness or consciousness. If you neglect that approach, you can lose the match! SYMPTOMS Mesial temporal sclerosis usually results in partial (focal) epilepsy. Febrile seizures. Also, the presence of bilateral mesial temporal sclerosis and additional extrahippocampal temporal abnormalities were not related to prognosis. I don’t want to hear the sound of T.V. For this procedure, the part of the brain containing the point at which the seizures start is removed. Depression 3.2. TLE is the most common form of epilepsy with focal seizures. There were also observations that hippocampal sclerosis was associated with vascular risk factors. Up to a third of patients with established refractory temporal lobe epilepsy have a history of seizures in childhood at the time of fever 3. Certainly the medicine had worked but the patient was still suffering, so now I decided to use the LM scale of potencies. Our offices are now open for in-person appointments. As of Jan 2015 he has got his job back and the last MRI done to see the vascularity of his brain was normal. This seizure disorder can cause a variety of symptoms such as strange sensations, changes in behaviour or emotions, muscle spasms, or convulsions and memory loss. Verbreitung. Lebensjahr auf. Temporal lobe epilepsy (TLE) is a chronic disorder of the nervous system characterized by recurrent, unprovoked focal seizures that originate in the temporal lobe of the brain and last about one or two minutes. Unaware of surroundings 3. Statistically, febrile seizure is the most strongly related to mesial temporal sclerosis symptomatology 12,14,16-18. In fact, 70 percent of temporal lobe epilepsy patients have some degree of mesial temporal sclerosis. The relationship, if any, of mesial temporal sclerosis with febrile seizures is controversial, made all the more difficult due to the relative insensitivity of imaging and the difficulty in establishing whether a particular seizure was truly febrile. It is a nice case well presented. Wave-like sensation which travels upwards and downwards to the left upper and lower limbs from the chest. Clinical manifestations Pre-existing complex febrile convulsions are common. In Nov 2014, there was a change of symptom picture. Causes and Symptoms of Mesial Temporal Sclerosis, Surgical Treatments for Mesial Temporal Sclerosis, Connect with our 7 convenient locations across Long Island, NY, strange sensations such as seeing auras or, Request a It also appears that the mesial temporal sclerosis can be worsened by additional seizures. A variety of epileptogenic agents administered to adult animals have resulted in MTS and spontaneous recurrent seizures. Now his symptoms were demanding another perfect match/simillimum. Lachesis LM2 was given twice a day for 4 days, after which he reported complete relief of the headache. If you can rationally think and catch the symptoms, you catch the remedy. He was again put on placebo, and he went on improving steadily till November 2014. Your selection of medicine is very accurate. He went on having the sensation for about 2-5 minutes and then it subsided , only to reoccur every 20- 30 minutes. Subscribe to world’s No. Jerking motion of the fingers 2.2. Before the seizure: 1.1. Had been excreting calculi from the urinary tract until one year ago. So, hippocampal sclerosis, mesial temporal sclerosis, could be easily scarred inside the temporal lobe. 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